Shared Facilities Research

Microscopy Imaging Core

Scientific Director:  Alistair Barber, PhD

The Microscopy Imaging Core includes a Leica SP2 TCS AOBS confocal system with an additional near-UV Laser and full live-cell incubation capacities; a complete Deconvolution Microscopy system using QED software; a custom-built fluorescence microscope with realtime multi-wave length acquisition (C&L Instruments); a Phillips Transmission Elect ron Microscope and full sample preparation services; and a complete Histology Services lab.

Services Offered:

·         Confocal Microscopy (FRET, FRAP, 3D reconstructions, etc.)

·         Deconvolution Microscopy

·         Transmission Electron Microscopy

·         Histology services (Sectioning and Mounting; Staining; Immunohistochemistry)

Major Equipment:

·         Leica TCS SP2 AOBS Confocal Microscope (with additional near UV laser, temperature and perfusion controlled Inverted stage 

·         Upright Leica fluorescence microscope with Retiga Exi high-speed CCD camera and Huygens software for deconvolution microscopy

·         Philips TEM 400 Electron Microscope

·         3 Sorvall Mt-2B ultramicrotomes

·         Durst enlarger

·         2 Leica cryocut 1800 cryostats

·         Histomatic tissue processor model 166 MP