Pediatric Surgeons of Central Pennsylvania

 

 







Contact Us

Research

Research

•  Grants and Support •  Publications
•  Educational Support for Students

Publications

Chinoy, MR. Lung Growth and Development.  A Review Article.   Front Biosci 8: 392-415, 2003. 

Volpe MV, Nielsen HC, Archavachotikul K, Ciccone TJ, and Chinoy MR.  Thyroid hormone affects cell fate and airway morphogenesis during late pseudoglandular period of mouse lung development.  Molec Genet Metab 80: 242-254, 2003. 

Mohideen M-APK, Beckwith LG, Tsao-Wu GS, Moore JL, Wong ACC, Chinoy MR and Cheng KC.  A histology-based screen for Zebrafish mutants with abnormal cell differentiation.  Dev Dyn 228: 414-423, 2003. 

Archavachotikul K, Ciccone TJ, Chinoy MR, Nielsen HC and Volpe MV.  Thyroid hormone affects embryonic mouse lung branching morphogenesis and cellular differentiation.  Am J Physiol  Lung Cell Mol Physiol 282: L359-LL369, 2002. 

Chinoy MR, Graybill MG, Miller SA, Kauffamn GL, Lang CM.  Angiopoietin-1 and vascular endothelial growth factor in vascular development and angiogenesis in hypoplastic lungs.   Am J Physiol Lung Cell Mol Physiol 283: L60-L66, 2002. 

Chinoy MR. Pulmonary Hypoplasia and Congenital Diaphragmatic Hernia:  Advances in Pathogenetics and Regulation of Lung Development.  A Review Article.  J Surg Res 106:209-223, 2002.  

Chinoy, MR, Nielsen, HC and Volpe, MV.  Mesenchymal nuclear transcription factors in nitrofen-induced hypoplastic lung.  J Surg Res 108: 203-211, 2002.

Chinoy MR, Chi X-L and Cilley RE.  Down-regulation of regulatory proteins for differentiation and proliferation in murine fetal hypoplastic lungs:  altered Mesenchymal-Epithelial Interactions.  Pediatr Pulmonol 32: 129-141, 2001.

Chinoy MR, Zgleszewski SE, Cilley RE, Krummel TM: Dexamethasone enhances ras-recision gene expression in cultured murine fetal lungs: implications in the regulation of lung development. Am J Physiol (Lung Cell Mol Physiol) 279(2): L312-8, 2000.

Cilley RE, Zgleszewski SE, Chinoy MR: Fetal lung development : airway pressure enhances the expression of developmental genes. J Pediatr Surg 35(1): 113-8; discussion 119, 2000.

Zhang L, Cilley RE, Chinoy MR: Suppression subtractive hybridization to identify gene expressions in variant and classic small cell lung cancer cell lines. J Surg Res 93(1):108-9, 2000.

Vyas SJ, Blaschak CM, Chinoy MR, Jackson EK.  Angiotensin II-induced changes in G-protein expression and resistance of renal microvessels in young genetically hypertensive rats.  Mol Cell Biochem 212: 121-129, 2000. 

Zgleszewski SE, Cilley RE, Krummel TM, Chinoy MR: Effects of dexamethasone, growth factors and tracheal ligation on development of nitrofen exposed hypoplastic murine fetal lungs in organ culture. J Pediatr Surg 34(8): 1187-95, 1999.

Chinoy MR, Cilley RE, Blewett CJ, Zgleszewski SE, Feinstein SI, Reisher SR, Krummel TM: Influence of epidermal growth factor and transforming growth factor beta-1 on patterns of fetal mouse lung branching morphogenesis in organ culture. Pediatr Pulmonol 25(4): 244-56, 1998.

Chinoy MR, Volpe MA, Cilley RE, Zgleszewski SE, Vosatka RJ, Martin A, Nielsen HC, Krummel TM: Growth factors and dexamethasone regulate Hoxb5 protein in cultured murine fetal lungs. Am J Physiol 274(4 pt 1): L610-20, 1998.

Zhang L, Zgleszewski SE, Cilley RE, Chinoy MR: Differential display of genes in normal and hypoplastic fetal murine lungs. J Surg Res 75(1):66-73, 1998.

Vyas SJ, Mokkapatti R, Dubey RK, Chinoy MR, Jackson EK: Guanine nucleotide-binding inhibitory protein-mediated inhibition of adenylyl cyclase is enhanced in spontaneously hypersensitive rat preglomerular arteriolar smooth muscle cells. J Pharmacol Exp Ther 285(2): 828-34, 1998.

Zgleszewski SE, Blewett CJ, Cilley RE, Krummel TM and Chinoy MR. Esophageal/ pyloric ligation enhances development of the murine fetal stomach in organ culture. J Pediatr Surg 33(3): 433-41, 1998.

Causak RA, Zgleszewski SE, Zhang L, Cilley RE, Krummel TM, Chinoy MR: Differential gene expression at gestational days 14 and 16 in normal and nitrogen-induced hypoplastic murine fetal lungs with coexistant diaphragmatic hernia.  Pediatr Pulmonol 26(5): 301-11, 1998.

Zgleszewski SE, Cilley RE, Krummel TM, Chinoy MR: Maintenance of fetal murine pulmonary microvasculature in heart-lung en bloc whole organ culture. J Pediatr Surg 32(8):1161-8, 1997.

Cilley RE, Zgleszewski SE, Krummel TM, Chinoy MR: Nitrofen dose-dependent gestational day-specific murine lung hypoplasia and left-sided diaphragmatic hernia. Am J Physiol 272(2 pt 1): L362-71, 1997.

Scarpelli EM, Moutone AJ, Chinoy MR, Defouw DO and Clutario BC: Intraalveolar bubbles and bubble films.   III.  vulnerability and preservation in the laboratory. Anat Rec 248: 498-520, 1997.

Cilley RE, Zgleszewski SE, Krummel TM, Chinoy MR: Acceleration of lung growth: the combination of dexamethasone and growth factors markedly enhances murine fetal lung development in vitro. Surgical Forum 47:692-5, 1996.

Blewett CJ, Zgleszewski SE, Chinoy MR, Krummel TM, Cilley RE: Bronchial ligation enhances murine fetal lung development in whole organ culture. J Pediatr Surg 31(7):869-77, 1996.

Scarpelli EM, Mautone AJ, Chinoy MR: Intraalveolar bubbles and bubble films. I.  formation and development during the first 48 hours of extrauterine life in rabbits. Anat Rec 244(3):344-57, 1996.

Chinoy MR, Gonzales LG, Ballard PL, Fisher AB, Eckenhoff RG: Elemental composition of lamellar bodies from human fetal lung explants. Am J Respir Cell Mol Biol 13(1):99-108, 1995.

Zepeda ML, Chinoy MR, Wilson JM: Characterization of somatic stem cells in human airway capable of reconstituting a fully differentiated bronchial epithelium. Somat Cell and Mol Genet 21(1):61-73, 1995.

Chinoy MR, Antonio-Santiago MT, Scarpelli EM: Maturation of undifferentiated lung epithelial cells into type II cells in vitro: Atemporal process that parallels cell differentiation in vivo. The Anat Rec 240:545-554, 1994.

Chinoy MR, Fisher AB, Shuman H: Confocal imaging of time-dependent internalization of NBD-PC and localization of intact rat lungs. Am J Physiol 266(6 pt 1):L713-21, 1994.

Chinoy MR, Dodia C, Fisher AB: Increased surfactant internalization by rat type II cells cultured on microporous membranes. Am J Physiol 264(3 pt 1):L300-7, 1993.

Kain ZN, Chinoy MR, Antonio-Santiago MT, Marchitelli RN, Scarpelli EM: Enhanced lung maturation in cocaine-exposed rabbit fetuses. Pediatr Res 29(6):534-7, 1991.

Back

 

 

 

Success Stories

 

For comments or suggestions send an email to pedsurg@hmc.psu.edu



Penn State Milton S. Hershey Medical Center ©2004
This page was last updated on August 11, 2005
Contact Us