Magnetic Resonance Spectroscopy (MRS)
MRS is used to study
neurochemicals and their changes due to diseases in a tissue
with NMR spectrum in vivo.
| Metabolite |
Peak(ppm) |
Concentration (mmol/kgww) |
Function |
|
NAA |
2.02 |
7.9 - 16.6 |
Neuronal marker |
| Choline |
3.2 |
0.9 - 2.5 |
Membrane turnover |
| Creatine |
3.0 |
5.1 - 10.6 |
Energy metabolism |
| Glutamate / Glutamine GABA |
2.2 - 2.4 |
6.0 - 12.5 |
Neurotransmitter |
| ml |
3.56 |
3.1 - 8.1 |
Glial marker |
In vivo neurochemical spectrum of the
putamen of a healthy young volunteer [voxel size=1.5×1.5×1.5cm3].
Abbreviations: Cr = Creatine, PCr = Phosphocreatine, Glx =
Glutamate + Glutamine, ml = Myo-inositol, Cho = Choline, Glu =
Glutamate, Gln = Glutamine, NAA = N-Acetylaspartate, MM =
Macromolecules.
|
