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Stem Cell Transplantation

What is Stem Cell Transplantation?

Stem Cell Transplantation (SCT) is a cancer treatment most often used for patients who have experienced a return of their cancer, known as relapse.  SCT makes it possible for patients to receive higher doses of chemotherapy and/or radiation therapy than would otherwise be possible and increases the likelihood that the cancer will be successfully controlled.

Bone marrow, located in the center part of the bones, is where blood cells are made. Stem cells are produced in the marrow and mature to become red blood cells, white blood cells and platelets. As they mature, they are released into the blood where they perform their specific functions.

In the process of stem cell transplantation, high doses of chemotherapy and/or radiation are given that destroy the bone marrow's normal production.  Stem cells that have been collected are then given back to restore the body's production.  

The stem cells can be obtained from different sources:

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For questions or comments regarding the Pediatric Hematology/Oncology web site, please email Linda Leonard  @ lleonard@psu.edu



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This page was last updated on November 08, 2006
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