Penn State Pediatric Hematology/Oncology

 
 

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Hematology/Oncology Research

The Penn State Pediatric Stem Cell Transplant Program is involved with national groups studying stem cell transplant and is a member of the Children's Oncology Group and Pediatric Blood and Marrow Transplantation Consortium.  The team also conducts research studies on cord blood transplants, sub-myeloablative transplants, and graft versus host disease (GVHD) treatment.

Current open studies

Principal Investigator

Title of Study

Kenneth Lucas, MD

The Use of Umbilical Cord Blood as a Source of Hematopoietic Stem Cells.

 Kenneth Lucas, MD

Normal Blood Donor Study.

 Kenneth Lucas, MD

Collection of Bone Marrow, Blood, or Tumor tissue banked through Human  tissue Network for Cryopreservation and Future lab Investigation from newly diagnosed or relapsed Ewing's Sarcoma & Neuroblastoma.

 Melanie Comito, MD

Dose intensive Chemotherapy for children less than 10 years of age - Newly diagnosed with malignant Brain Tumor,

Kenneth Lucas, MD

A phase I study to examine the toxicity of allogeneic stem cell transplantation  for Pediatric solid tumors with relapsed or therapy refractory disease.

Melanie Comito, MD

High dose temozolomide, thiotepa and carboplatin with autologous stem cell rescue (ASCR) followed by continuation therapy with 13-cis-retinoic acid in patients with recurrent/refractory malignant brain tumors.

Kenneth Lucas, MD

A Phase I Trial to Examine the Safety, Clinical, Immunologic and Virologic
Effects of CMV pp65 Specific Cytotoxic T Lymphocytes for Recipients of 
Allogeneic Stem Cell Transplants with Persistent or Therapy Refractory
Infections.

Kenneth Lucas, MD

 
A Phase I-II Randomized Trial to Examine the Clinical, Immunologic, and
Virologic Effects of CMV Specific Cytotoxic T Lymphocytes When Used for
Prophylaxis Against CMV Disease in Recipients of Allogeneic, T Cell
Depleted Stem Cell Transplants.
 

John Neely, MD

A Randomized Trial of Sirolimus-Based Graft versus Host Disease (GVHD) Prophylaxis after Hematopoietic Stem Cell Transplantation (HSCT) in Relapsed Acute Lymphoblastic Leukemia (ALL).

For questions about these or other studies, please contact Swati Shah at (717) 531-6012.

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For questions or comments regarding the Pediatric Hematology/Oncology web site, please email Linda Leonard  @ lleonard@psu.edu



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This page was last updated on February 05, 2008
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