Allogeneic Stem
Cell Transplantation
Allogeneic
means “from another person”. Stem cells for this type of transplant are
obtained from a variety of sources.
-
Matched
related donors (MRD) are usually siblings whose stem cells are most
similar to those of the patient.
-
Some
patients will receive stem cells from a partially matched related donor,
such as a parent.
-
The
National Donor Registry provides information to find a matched unrelated
donor (MUD) from a pool of adults who donate their stem cells for
transplantation.
-
Umbilical
cord blood can also be used and can be located through National
Registries.
The
Penn State Children’s Hospital Transplant team performs allogeneic transplants
for diseases such as
-
Acute
lymphoblastic leukemia (ALL)
-
Acute
myelogenous leukemia (AML)
-
Chronic
myelogenous leukemia (CML)
-
Myelodysplastic
syndrome (MDS)
-
Juvenile
myelomonocytic leukemia (JMMoL)
-
Lymphoma
-
Aplastic
anemia
-
Disorders
of the immune system
-
Storage Disease
-
Hemoglobin
disorders such as sickle cell anemia and Beta-thalassemia
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