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Neuroblastoma
The
successful treatment of neuroblastoma requires a multi-disciplinary approach
involving chemotherapy, surgery, radiation and stem cell transplantation.
In general, patients undergo stem cell collection after three cycles of
chemotherapy, and the stem cells are frozen for later use.
After
further chemotherapy, surgery is performed to remove any tumor that
remains. High dose chemotherapy with carboplatinum, melphalan, and
etoposide is given followed by an infusion of the patient's own stem
cells. Radiation therapy is generally given within 30-60 days following
the stem cell transplant. Patients then receive retinoic acid therapy.
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