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Hypothyroidism

Also known as:  Underactive Thyroid

What is it?

Hypothyroidism develops when the thyroid gland doesn’t produce enough thyroid hormone. Too little hormone slows down all the chemical reactions in the body, leading to life-threatening complications.

Who gets it?

Hypothyroidism is one of the most common chronic diseases in the United States, affecting an estimated 11 million adults and children. As many as two of every three people with hypothyroidism may not know they have the disease. The condition can develop in anyone, though hypothyroidism tends to run in families. Middle-aged and elderly women are the most commonly affected. Factors that increase a person's risk of developing hypothyroidism include age, weight, and medical history.

What causes it?

Hypothyroidism is most often the result of Hashimoto's disease, also known as chronic thyroiditis (inflammation of the thyroid gland). In this disease, the immune system fails to recognize that the thyroid gland is part of the body's own tissue and attacks it as if it were a foreign body. The attack by the immune system impairs thyroid function and sometimes destroys the gland. Other causes of hypothyroidism include radiation, surgery, viruses and bacteria, certain medications, pituitary gland malfunction, diet, environmental contaminants, or a congenital defect.

What are the symptoms?

Patients who complain of fatigue, constipation, dry skin, depression and high diastolic blood pressure are likely to have hypothyroidism, particularly if the symptoms occur together and are persistent. The patient may also experience decreased heart rate, progressive hearing loss, weight gain, problems with memory and concentrations, and an enlarged thyroid gland (goiter).

How is it diagnosed?

Hypothyroidism is diagnosed by testing the patient’s blood to measure the level of both thyroid hormone and the pituitary’s thyroid-stimulating hormone (TSH). A thyroid nuclear medicine scan and thyroid ultrasound may also be used to confirm the diagnosis.

What is the treatment?

Patients diagnosed with hypothyroidism are prescribed a synthetic thyroid hormone tablet that will most likely need to be taken every day for the rest of the patient’s life. It may take several months to determine the correct dosage, however patients usually start to feel better within 48 hours. Regular exercise and a high-fiber diet can help maintain thyroid function and prevent constipation. Alternative treatments are primarily aimed at strengthening the thyroid and will not eliminate the need for thyroid hormone medications. Herbal remedies to improve thyroid function and relieve symptoms of hypothyroidism include bladder wrack (Fucus vesiculosus), which can be taken in capsule form or as a tea. Some patients may need to undergo surgery to treat hyperthyroidism. Patients requiring surgery suffer from large goiter and relapses, even after repeated attempts to address the disease through drug therapy.


This information has been designed as a comprehensive and quick reference guide written by our health care reviewers.  The health information written by our authors is intended to be a supplement to the care provided by your physician.  It is not intended nor implied to be a substitute for professional medical advice. 

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This page was last updated on October 31, 2006
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