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Hand Dermatitis

Also known as: Eczema

What is it?

Hand dermatitis is an inflammation of the skin on the hands that occurs when the hand touches a substance that is an irritant or triggers an allergic reaction.

Who gets it?

Hand dermatitis is a common skin condition. People whose professions put them in frequent contact with wet or irritating substances, such as cleaning fluids, nail polish remover, and other chemicals; people who wash their hands repeatedly; and those whose work requires frequent contact with metals are at an increased risk of developing this condition.

What causes it?

Hand dermatitis can be caused by contact with an irritant, an allergic reaction to a substance, or an inherited condition. Irritant contact dermatitis (ICD) of the hands is most often caused by detergents, certain types of metals, soaps, strong chemicals, and solvents that, either immediately or after repeated exposure, irritate the skin. These substances can break down the skin’s natural barrier of protection. Other irritants include repeated friction, wind, and cold. Allergic contact dermatitis (ACD) of the hands occurs when a substance called an allergen triggers the body’s immune response. The immune system produces antibodies and other disease fighting cells in response to the allergen. The antibodies release chemicals that actually injure the surrounding cells and cause the physical symptoms of an allergic reaction. The most common causes of ACD are latex, found in medical gloves and condoms; fragrances and other substances found in cosmetics and skin creams; metals, such as nickel found in jewelry; plants, such as poison ivy, poison oak, and poison sumac; and chemicals used in the clothing manufacturing process. You can have an allergic reaction to a substance after repeated exposure, even though it never caused a reaction before. The tendency to have some forms of hand dermatitis can be inherited at birth. These patients are likely to have certain hypersensitivity reactions, such as asthma or hay fever, when exposed to specific triggers called antigens. This is called atopic hand dermatitis. Certain types of fungal infections, such as tinea pedis, can also cause hand dermatitis.

What are the symptoms?

The symptoms of hand dermatitis can range from a mild, itchy rash to severe itching, swelling, and blistering. In severe cases, open sores can result in bacterial skin infections. Irritant contact dermatitis usually affects the top of the hand, often appearing as dry, chapped skin around the knuckles and tops of the fingers. If caused by metals, the irritation appears under a ring. Allergic contact dermatitis also usually appears on the top of the hand and around the fingers. Contact with a poisonous plant causes blistering and weeping, while other types of allergic contact dermatitis may cause a chronic skin rash. Atopic hand dermatitis also causes a chronic rash. When hand dermatitis is caused by a fungal infection, the symptoms include itchy blisters along the sides of the fingers.

How is it diagnosed?

Hand dermatitis is diagnosed according to a pattern of symptoms. Your doctor will take a complete medical history and ask you questions about the types of substances you have regular contact with or had contact with right before the symptoms appeared, how long your symptoms have been occurring, and whether you have eczema on other parts of your body. If your doctor suspects allergic contact dermatitis, but it is difficult to identify the allergen, he or she may perform a patch test. The doctor will place a small patch on your skin for a period of two days. The patch contains some common allergens that cause contact dermatitis of the hand. After the patch is removed, the doctor will check for a reaction over the next few days.

What is the treatment?

To treat hand dermatitis, you must avoid contact with the substance that irritates your skin. Your doctor can recommend ointments or lotions, usually topical corticosteroids, to relieve itching and irritation until the symptoms go away. He or she will also recommend that you keep your hands well lubricated and try not to wash your hands too frequently. If you have severe swelling and/or itching, your doctor may prescribe oral corticosteroids or antihistamines, as well as medicated soaks to dry out the blisters. Antibiotics are prescribed for bacterial skin infections.

Self-care tips

Avoid any substances that you know irritate your skin or trigger an allergic reaction. In some cases, washing thoroughly with soap and water after contacting a substance, such as a poisonous plant, can prevent or minimize symptoms. If your profession requires frequent exposure to water, chemicals, cold, or friction, wear waterproof gloves or heavy work gloves to protect the hands.


This information has been designed as a comprehensive and quick reference guide written by our health care reviewers.  The health information written by our authors is intended to be a supplement to the care provided by your physician.  It is not intended nor implied to be a substitute for professional medical advice. 

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