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Basal Cell Carcinoma

What is it?

Basal cell carcinoma is the most common form of skin cancer. Basal cell carcinoma is named for the basal cells from which it develops, which are located at the bottom of the outer skin layer (epidermis).

Who gets it?

Basal cell carcinoma affects approximately 800,000 Americans each year. Anyone with a history of frequent sun exposure can develop basal cell carcinoma. People who do not tan easily, such as those with fair skin, light hair, and blue, green, or gray eyes, are at highest risk. Until recent years, basal cell carcinomas most commonly affected older people, particularly men who had worked outdoors. However, healthcare professionals are seeing more women develop these lesions, and both men and women are developing them at an earlier age. This is most likely from purposeful tanning during the teenage years and more time spent outdoors enjoying leisure activities.

What causes it?

Exposure to sunlight is the cause of almost all basal cell carcinomas, which almost always occur on sun exposed portions of the body -- the face, ears, neck, scalp, shoulders, and back. Rarely, tumors can develop on non-exposed areas. In a few cases, contact with arsenic or exposure to radiation can be contributing factors.

What are the symptoms?

The most typical appearances of basal cell carcinoma are:

  • An open sore that bleeds, oozes, or crusts and remains open for three or more weeks.
  • A reddish scaly patch or irritated area, frequently occurring on the chest, shoulders, arms, or legs. Sometimes the patch may itch or hurt. More commonly, it persists with no noticeable discomfort.
  • A shiny bump or nodule that is pearly or translucent. It may also be pink, red, or pigmented, especially in dark-complected people.
  • A scar-like area that is white, yellow, or waxy, and often has poorly defined borders. The skin itself appears shiny and tight. Although this is a less frequent sign, it can indicate the presence of an aggressive tumor.

How is it diagnosed?

To make a diagnosis of skin cancer, your doctor will take a complete medical history and also question you about your sun exposure habits along with your personal and family history of skin cancer. The doctor will then need to know when the mark appeared, whether it has changed in size or appearance, and if it has been treated before. Next, he or she will perform a skin examination. If your doctor finds any cause for concern, he or she will recommend a skin biopsy. This procedure is performed in the doctor's office with a local anesthetic. The portion of skin that is removed with the biopsy is sent to a dermatopathologist, who will examine it under a microscope and determine if any cancer is present.

What is the treatment?

The majority of basal cell carcinomas are highly curable with both surgical and non-surgical therapy. The exact method chosen will depend on the tumor's location and size along with the your general health, medical history, and whether the tumor has been treated before. There are many treatment options. Curettage and electrodessication is highly effective for small, well-defined, nonaggressive tumors. With this procedure, the doctor uses a semi-sharp instrument with spoon-shaped edge (called a curette) to scrape away tumor tissue. Then, the area is treated with an electric needle that generates enough heat to destroy any residual cancer cells that might remain. The wound will usually heal within a few weeks. Radiation therapy can be useful for tumors that have spread into the lymph nodes. It may also be used for patients whose medical condition will not allow him or her to under go surgery. Unfortunately, radiation therapy can cause skin cancer many years after treatment and the appearance of irradiated skin can deteriorate over time. For these reasons, radiation therapy is generally not recommended for young patients. Cryosurgery uses very cold liquid nitrogen to freeze the tumor and kill the cancer cells. The tissue then blisters off in a few days and the wound heals on its own in a few weeks. It is most effective for superficial or small lesions. With a procedure called standard excision, the skin is numbed before the tumor is cut away with a 3 to 4 millimeter border of normal skin. Standard excision is most effective for tumors that have well-defined borders and have not been treated before. Mohs’ micrographic surgery is a highly specialized technique in which a trained Mohs’ micrographic surgeon removes tumor tissue surgically layer by layer, mapping each layer and examining the excised tissue for residual tumor cells under a microscope. If residual tumor cells are identified, its location is precisely mapped and an additional layer of tissue is removed at that exact location. By examining 100% of the margins, it provides the highest cure rate of all therapies for basal cell carcinoma.

Self-care tips

The best way to prevent skin cancer is to protect you and your family from excessive exposure to sunlight. 80% of your lifetime sun exposure occurs before you are 20 years old. Therefore, both adults and children need to be protected from sunburn by appropriate clothing, hats, sunscreen and avoiding the mid-day sun. It is important to have a full skin examination performed by a qualified physician on a regular basis. You should also learn the signs of basal cell carcinoma, and examine your own skin regularly -- as often as once a month if you are at high risk. Be sure to include the scalp, backs of ears, neck, and other hard-to-see areas. (A full-length mirror and a hand-held mirror can be very useful). If you observe any of the warning signs or some other change in your skin, consult your physician immediately.


This information has been designed as a comprehensive and quick reference guide written by our health care reviewers.  The health information written by our authors is intended to be a supplement to the care provided by your physician.  It is not intended nor implied to be a substitute for professional medical advice. 

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This page was last updated on October 31, 2006
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