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The CEL contracts with pharmaceutical companies to evaluate the efficacy and safety of drugs that target endocrine based diseases. These studies have largely focused on steroid biochemistry and the determination of blood and urine estradiol and estrone levels using ultra-sensitive methods to detect the suppressed, postmenopausal levels. Several Phase I and Phase III studies have been carried out with companies such as Ciba Geigy, US Bioscience, Zeneca, Merrel Dow and Pharmacia. These projects examined the efficacy and potency of aromatase inhibitors used for second line therapy of breast cancer. The CEL staff is experienced in all aspects of clinical trial hormone analysis and is able to customize its support for each individual study. Please learn more about some specific drug studies that the CEL was involved in by visiting the Projects/Contracts section. The CEL also functions as a trial site for Pre-FDA approval evaluation of instruments and reagents for diagnostic companies. Abbott Laboratories, Dupont, Behring Diagnostics, Johnson & Johnson Clinical Diagnostics, INCstar and Hybritech are a few companies that have contracted testing and evaluation support from the CEL.
The Core Endocrine Laboratory Web site is maintained by Christopher Hamilton ![]()