Research

Low Dose Naltrexone Therapy for Crohn's Disease

Dr. Jill Smith is currently enrolling patients in a 4 month study to test the effectiveness of a low dose of naltrexone in offering relief to patients suffering from symptoms of Crohn's Disease.

Eligibility Criteria

• 18 years of age
• Have endoscopic or x-ray confirmed active Crohn's disease
• Have normal liver enzymes
• Not have a surgical ostomy or ileocolic anastomosis
• Not take tacrolimus, cyclosporin, mycophenolate or Infliximab for 4 weeks prior to entering study

Study Protocol

Participants will have a complete physical, blood work taken, keep symptom diaries, complete questionnaires and continue with follow-up for 4 months.

Cost of medication, office visits, and blood work are paid by the study. This research has been approved by the Institutional Review Board, under FDA regulations, at Penn State's College of Medicine.

Interested patients contact Sandra Bingaman, R.N. at 717-531-8108.