IRB Number
|
# 19286
|
| Description |
We are investigating whether the
drug, atorvastatin, will lower cholesterol levels, improve the function of
blood vessels, decrease circulating male hormone levels, and improve
symptoms in women with PCOS. |
| What is expected of me? |
Medical history and physical,
blood work, questionnaires, transvaginal ultrasound, electrocardiogram,
comprehensive blood pressure measurements (consisting of continuous blood
pressure, heart rate and blood flow monitoring during baseline and final
testing), urine diary and daily collection of urine samples, oral glucose
tolerance test, taking study medication or placebo |
| Inclusion Criteria |
- 18 to 40 years of age
- PCOS
- LDL cholesterol greater than 100 mg/dL
|
| Exclusion Criteria |
- Pregnant
- Lactating
- Taking hormonal contraception (within last 3 months)
|
| Length of Study |
There will be approximately 3
visits over a six-week period. The screening visit will be around 30 minutes
The baseline and final visits last about 4-5 hours. |
| Study Location |
Penn State Milton S. Hershey
Medical Center |
| Investigator Information |
Richard S. Legro
M.D.Department of OB/GYN |
| To obtain more information about this study please contact: |
Nazia Raja-Khan
M.D.Dept of Medicine, Division of Endocrinology
717-531-8395 |
