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Penn State Pediatric Nephrology

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Article from the Journal of American Medical Association


Urinary Tract Infections

What is it?

The urinary tract consists of the kidneys, ureters, bladder and urethra. The kidneys filter waste materials from the blood and these waste materials become urine. The ureters carry the urine from the kidneys tothe bladder where it is held until you go to the bathroom. The tube that carries the urine from the bladder to the outside of your body is called the urethra. Under normal circumstances no bacteria grow in the urine. When bacteria start to grow in the urine we call this a urinary tract infection.

Urinary tract infections can be limited to the bladder or they can affect the bladder and kidney, a more serious condition called a kidney infection or pyelonephritis. The younger the child is the more difficult it is to tell the difference between simply a bladder infection and the more serious pyelonephritis.

Who gets it?

About 5% of girls get urinary tract infections sometime before they graduate from high school. After the first year of life is rare for boys to get a urinary tract infection. The reason girls are more likely to have urinary tract infections is that their shorter urethras make it easier for bacteria to get into the bladder.

What causes it?

Urinary tract infections are most often caused by bacteria but may rarely because by viruses, fungi or some types of parasites. The most common causes of a urinary tract infection are the bacteria present in the digestive system and on the skin around the rectum and the vagina. This bacteria can travel up through the urethra into the bladder and cause an infection there. Occasionally this infection can travel up to the kidneys infecting them as well. Urinary tract infections may also be caused by bacteria that directly reach the kidney by traveling through the blood stream.

What are the symptoms?

In infants specific symptoms may be difficult to detect. Your baby will not be able to tell you that it hurts to urinate. He or she may have a high fever, may be irritable and not feed or drink. Occasionally they may develop diarrhea. Newborn babies who develop kidney infections may be unable to clear the yellow color (jundice) from their skin that babies often get shortly after birth.

Older children with bladder infections may tell you that they have a burning sensation or pain when they urinate. These children often need to go to the bathroom frequently and may lose control and wet themselves before they can get to the toilet. Sometimes they may again begin wetting the bed.

If your child has a kidney infection they may develop a high fever, back pain and generally feel quite sick. In any of these presentations, the urine may become cloudy and had a strong odor.

How is it diagnosed?

Your doctor will need to examine your child urine to be certain of the diagnosis. In older patients it may be possible to clean the child's penis or vagina and collect the urine as child urinates into a sterile container. In small infants, particularly girls, it may be necessary to put a thin, sterile plastic to through the urethra into the bladder. This is done to be certain that the urine collected is not contaminated with the infants stool. The urine is then examined under the microscope and more importantly, sent to the laboratory to try and grow the bacteria. This is an important step in making the diagnosis and should not be left out.

What is the treatment?

Urinary tract infections are usually easy to treat, but it's important to begin treatment right away. Bacterial urinary tract infections need to be treated with an antibiotic. Your doctor will have to choose between an oral antibiotic and giving the medicine to your child as an intravenous infusion. The choice will depend on whether the infection is limited to the bladder or involves the kidney and how sick here child-appears to be. It's also helpful to increase your child's fluid intake to help the washout the bacteria from the bladder and prevent dehydration.

Once you child has completed treatment it may be necessary for your doctor to order additional tests to be certain that your child's kidneys, ureters and bladder are functioning correctly. Particularly in younger children your doctor will often order a renal and bladder ultrasound. This test allows the doctor to be certain that the organs are formed normally. In addition, most physicians will obtain a voiding cystourethrogram. This test involves putting a thin, sterile plastic tube into your child's bladder and filling of the bladder with some radiology dye. The radiologist then takes pictures of the dye in the bladder to be certain that the bladder is formed correctly and that the dye in the bladder doesn't go back up into the kidneys. If this happens your doctor may have to suggest other treatments to prevent future kidney infections.

Self-care tips

You can help prevent urinary tract infections by making sure you always empty your bladder completely when you go to the bathroom. Drink plenty of fluids and don't hold your urinated for long periods of time. If you are a girl, always liked from front to back seat old spread bacteria from your rectum to your urethra. Keep your genital area clean and dry, and avoid irritating substances like bubble baths and products that have strong fragrances added. If you are sexually active, make sure you wash your genital area and urinate after intercourse. This will help to remove any bacteria that can travel up the urethra.


This information has been designed as a comprehensive and quick reference guide written by our health care reviewers.  The health information written by our authors is intended to be a supplement to the care provided by your physician.  It is not intended nor implied to be a substitute for professional medical advice.

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This page was last updated on October 31, 2006
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