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Inflammatory Bowel Disease (IBD) in Children

What is it?

Inflammatory bowel disease (IBD) is a general name for diseases that cause the intestine to become inflamed, causing abdominal cramps and diarrhea. The two most common forms of IBD are Crohn’s disease and ulcerative colitis. Crohn’s disease usually occurs in the lowest part of the small intestine, called the ileum, as well as the large intestine. However, it can affect any part of the digestive tract, from the mouth to the anus. Crohn's disease is sometimes called ileitis or enteritis. With ulcerative colitis, only the inner lining of the large intestine becomes inflamed, swollen, and ulcerated. The inflammation usually begins in the lower end of the large intestine, called the sigmoid colon, which empties into the rectum. When the rectum and large intestine become inflamed, water can’t be absorbed into the blood stream, which causes diarrhea. Eventually, the inflammation spreads throughout the large intestine, with the exception of the last section called the ileum. The small intestine is not affected in ulcerative colitis.

Who gets it?

Both boys and girls can get an IBD. If someone in your family suffers from an IBD, other family members have a 20% chance of also having the disease. Most people are diagnosed between the ages of 15 and 40.

What causes it?

No one is sure what causes IBD. However, researchers believe it may be caused by an overactive immune response in the intestine. The immune system attacks the intestine, which causes the inflammation. Some researchers believe some type of viral, bacterial, or fungal organism sets off the cycle of the ulcerative colitis. IBD is not contagious, however.

What are the symptoms?

The most common symptoms of an IBD are abdominal pain and diarrhea. Symptoms may be mild and come and go. In some cases, symptoms are severe and include fever, bloody stools, weight loss, anemia, and fatigue. Symptoms of Crohn’s disease in children generally include joint pain, fever, anemia, and slow growth. Other complications of Crohn’s and ulcerative colitis can include ulcers in and around the mouth, skin rashes, and eye inflammation. These symptoms improve with treatment of the intestinal inflammation.

How is it diagnosed?

An IBD is diagnosed by taking a thorough medical history and detailed list of symptoms. Because the inflammation of the intestine can be caused by disorders other than ulcerative colitis, stool and blood samples are important methods to determine whether the symptoms are caused by a bacterial or parasitic infection. Blood tests may also reveal anemia in cases of severe blood loss. The best way to confirm a diagnosis and locate the area of infection is through a procedure called endoscopy. A tiny, flexible viewing tube inserted through the rectum and into the colon lets the doctor examine the lining of the intestine. He or she can also take a small sample (biopsy) of the intestine to examine under a microscope for inflammation. An endoscopy is usually performed under general anesthesia. Your doctor may also order a barium x-ray after treatment has begun to get a better view of the intestine. Barium is a chalky liquid that your child will either drink or have inserted as an enema through a tube in the rectum before the x-ray.

What is the treatment?

There is no true cure for IBD, although severe cases of ulcerative colitis can be cured by removing the colon. Treatment is aimed at controlling and reducing symptoms. Treatment usually begins with some type of oral drug, such as sulfasalazine or mesalamine, which reduces inflammation and helps stop flare-ups. These drugs can be given as pills, liquids, and, sometimes, suppositories. Children who don’t respond to these drugs may be given steroid medications, such as prednisone. If prednisone is used, the goal is to slowly reduce and then stop the steroid and continue the sulfasalazine or mesalamine. It’s best to avoid foods that irritate the intestines, such as nuts, popcorn, or raw vegetables. Doctors frequently recommend nutritional supplements and special high-calorie liquid formulas, especially for children with delayed growth. In severe cases, children may need to be hospitalized. Treatment might include a nasogastric tube for removal of stomach juices and for feeding, intravenous fluids for dehydration, and antibiotics to fight infection. Surgery is recommended only in severe cases where other treatments are not working or in cases where your child’s growth is substantially delayed. Surgery for ulcerative colitis involves removing all or most of the large intestine. While the intestine heals, the intestine

temporarily drains stool through an opening in the abdomen called a stoma. A special bag placed over the opening collects the liquid stool. Usually, the stoma is temporary. After the intestine has healed, another surgery will reconnect the remaining intestine to the rectum so that normal bowel movements can resume. In Crohn's disease, the surgeon usually removes the diseased section of the intestine and joins the remaining healthy sections together. However, while surgery may relieve symptoms of Crohn’s disease indefinitely, it is not a cure. The inflammation tends to return next to the area of intestine that has been removed.

Self-care tips

If your child has been diagnosed with an IBD, it’s important to follow your doctor’s recommended treatment plan. Report any changes in your child’s condition immediately, provide your child with a healthy diet, and make sure he or she gets plenty of rest. It’s important to make the school nurse and teachers aware of your child’s condition so he or she is able to use the bathroom as often as necessary. Children with an IBD can participate in normal activities as long as they are feeling well.


This information has been designed as a comprehensive and quick reference guide written by our health care reviewers.  The health information written by our authors is intended to be a supplement to the care provided by your physician.  It is not intended nor implied to be a substitute for professional medical advice.

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This page was last updated on October 31, 2006
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