Penn State Children's Hospital
Calendar  I  Contact Us  I  Help  I  Search
 
  1-800-243-1455
 

 

 

Health & Disease Information

 
 

A   B   C   D   E   F   G   H   I   J   K   L   M   N   O   P  Q   R   S   T   U   V   W   X   Y   Z

 
 

Bipolar Disorder

What is it?

Bipolar disorder, also known as manic-depressive disorder, is a serious mental illness marked by mood shifts and episodes of depression and mania. The Diagnostic and Statistical Manual of Mental Disorders lists four separate categories of bipolar disorder: bipolar I, bipolar II, cyclothymia, and bipolar not-otherwise-specified (NOS).

Bipolar I is marked by manic episodes followed by periods of depression that may not be severe. In contrast, Bipolar II is marked by major depressive episodes and hypomanic periods, or milder episodes of mania. Cyclothymia is defined as episodes of hypomania and depressive periods that do not reach major depressive proportions. Bipolar NOS means that the bipolar state does not fit into the other categories.

Who gets it?

Both children and adults may develop bipolar disorder but most commonly, the disorder develops from adolescence through the early twenties. Studies have shown that people who have family members with emotional disorders may be more susceptible to bipolar disorder. Many patients with bipolar disorder have a history of substance abuse. A possible biological cause is the presence of calcium build-up in the cells of bipolar patients. Bipolar disorder is just as prevalent among women as men although their symptoms may vary.

What causes it?

There is no clear cause of bipolar disorder. It may be genetic, the result of substance abuse – especially cocaine – or caused by the presence of calcium build-up in the cells.

What are the symptoms?

Children may display symptoms in different ways than adults. When manic, children and adolescents may be irritable and have destructive outbursts rather than elation or euphoria like their adult counterparts.

Children may complain of headaches, muscle aches or stomachaches when in a depressive state. Also, performance at school may suffer, they may talk about running away from home, become isolated, be extremely sensitive to rejection and have periods of unexplained crying.

Whereas adult-onset bipolar disorder may be more patterned, childhood- or early adolescent-onset bipolar disorder may be rapid-cycling, meaning the episodes of depression and mania may shift more frequently. The childhood or early adolescent-onset bipolar disorder may even be more severe.

Diagnosis

A psychiatrist or psychologist usually diagnoses bipolar disorder. Interviews and tests may be used and, because of the complexity of the disorder, it may take several visits, and sometimes months or years, to definitively diagnose a patient with bipolar disorder.

Treatment

Bipolar disorder is treated with medications including a combination of mood stabilizing agents, anti-depressants, anti-psychotics and anticonvulsants. An individualized combination of the medications is determined in order to regulate the patient’s manic and depressive episodes. Psychotherapy and counseling may be used in combination with medications.

Electroconvulsive therapy can be used as a treatment for unipolar and bipolar depression and mania. Because of the stigma attached to ECT, it is often used after medication options are explored. ECT is given under anesthesia and muscle relaxants are used to prevent convulsions. The exact reasons ECT works is unknown, but it seems that the electrical currents sent to the brain alter the electrochemical processes of the brain and, consequently, relieve depression.

Whereas many patients respond to medications, ECT and psychotherapy, a small number of those suffering with bipolar disorder don’t respond to any treatments. Generally, bipolar disorder requires lifelong treatment.


This information has been designed as a comprehensive and quick reference guide written by our health care reviewers.  The health information written by our authors is intended to be a supplement to the care provided by your physician.  It is not intended nor implied to be a substitute for professional medical advice.

Back

 
   



Penn State Milton S. Hershey Medical Center ©2004
This page was last updated on October 31, 2006
Contact Us